5 Easy Facts About LDN-27219 side effects Described
1 significantly attention-grabbing compound is LDN-27219. When most tTG inhibitors are built to bind on the protein crosslinking active site, LDN-27219 alternatively binds on the nucleotide binding pocket in the enzyme whilst it is actually in its closed-point out conformation, and stabilizes that conformation to forestall crosslinking activity.78